NL-OMON40345
已完成
不适用
The role of neutrophil extracellular trap formation in sickle cell disease - NET, in-vitro experiments
概览
- 阶段
- 不适用
- 干预措施
- 未指定
- 疾病 / 适应症
- sickle cell
- 发起方
- Academisch Medisch Centrum
- 入组人数
- 30
- 状态
- 已完成
- 最后更新
- 2年前
概览
简要总结
暂无简介。
研究者
入排标准
入选标准
- •For patients:
- •1\. High performance liquid chromatography confirmed diagnosis of HbSS, HbSC, HbS\*0\- or HbS\*\+\-thalassemia genotype in SCD patients. 2\. Written informed consent by the patient. 3\.18 years and older
- •For healthy volunteers:
- •1\. Age \* 18 years; 2\. WHO performance score 0; 3\. healthy race\-matched family member or acquaintance
排除标准
- •For patients
- •1\. HbSC or HbS\*\+\- thalassemia genotype . 2\. Pregnancy 3\. Active cancer 4\. Chronic HIV infection 5\. Recent vaso\-occlusive crisis (\< 1 months) 6\. Chronic transfusion therapy 7\. Recent blood transfusion (\< 3 months)
- •For healthy volunteers:
- •Carrier of sickle cell gene or other hemoglobinopathy
结局指标
主要结局
未指定
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