The optimal dose of dexmedetomidine for reduce the postoperative catheter related bladder discomfort in post-anesthesia care unit
Phase 4
Completed
- Conditions
- Catheter-related bladder discomfort (CRBD) is defined as an urgent urination or a burning sensation in the suprapubic area. A study showed that 55% of the patients in the post-anesthesia care unit (PACU) experienced moderate or severe CRBD symptoms. CRBD leads to restlessness and agitation and it also enhances the risk of falling out of bed.Moreover, it may increase the workload of nursing staff in the PACU. Therefore, early management of CRBD during anesthesia recovery is clinically significant.Dexmedetomidine, catheter-related bladder discomfort, pharmacology
- Registration Number
- TCTR20220407005
- Lead Sponsor
- The Quzhou Affiliated Hospital of Wenzhou Medical University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 29
Inclusion Criteria
American Society of Anesthesiologists (ASA) I-II
patients between 18 and 80 years in the PACU after general anesthesia
diagnosed Catheter-related bladder discomfort
Exclusion Criteria
Patients with a history of bladder outflow obstruction, urinary tract infection, neurogenic blad-der, chronic analgesic abuse, severe hepatic or renal disease, arrhythmia, and morbid obesity were excluded from this trial.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The severity of CRBD 30 min after dexmedetomidine administration Scale to assess
- Secondary Outcome Measures
Name Time Method adverse effects 30 min after dexmedetomidine administration Major adverse effects of dexmedetomidine including hypotension, hypertension, bradycardia, and sedation were monitored and recorded.