Effects of Transcutaneous Electrical Acupoint Stimulation Combined With Transverse Abdominis Plane Block on Perioperative Pain and Early Postoperative Recovery in Patients Undergoing Laparoscopic Cholecystectomy
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 120
- 主要终点
- VAS(visual analogue scale) score
研究概览
简要总结
To explore the application of transcutaneous electrical acupoint stimulation combined with transverse abdominis plane block in Laparoscopic cholecystectomy, in order to reduce postoperative pain and promote postoperative recovery.
详细描述
Percutaneous electrical acupoint stimulation has been applied in preoperative prophylaxis, intraoperative anesthesia and postoperative rehabilitation, and can reduce perioperative anxiety, improve the efficacy of preoperative smoking cessation and alcohol abstinence, and shorten the preoperative fasting time. During surgery, it can reduce the amount of anesthetic drugs, anti-inflammatory and anti-stress effects, stabilize circulation, and protect important organs; After surgery, improve the speed and quality of wake-up of patients, promote the recovery of maintenance function, regulate immune function, and reduce postoperative adverse reactions such as postoperative pain, postoperative nausea and vomiting, postoperative urinary retention, etc. As one of the common nerve blocks, transverse abdominis block is used clinically, and its main function is to relieve perioperative pain and reduce the amount of traumatic stress and analgesic drugs
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Double (Participant, Outcomes Assessor)
盲法说明
Data collector
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •American Society of Anesthesiologists (ASA) class I and II
- •Age 18-65 years
- •Laparoscopic cholecystectomy for the first time
- •There is no rupture, infection in the acupoint pasting site
- •The patient knows and signs the informed consent form
排除标准
- •People with visual impairment, hearing impairment and alcoholism
- •History of diabetes, myocardial infarction or cerebrovascular accident, liver and kidney dysfunction
- •Those who are allergic to non-steroidal drugs, anticholinergic drugs, and anesthetic drugs
- •Those who are unable to cooperate or refuse to participate in the research or request to withdraw during the research process
- •Those with contraindications to percutaneous electrical stimulation, including local skin damage, infection or implantation of electrophysiological devices in the body
结局指标
主要结局
VAS(visual analogue scale) score
时间窗: After the operation 48hour
Postoperative pain is assessed after surgery by using visual analogue scoring. A score to assess pain, use a swimming ruler about 10 cm long, marked with 10 scales on one side, with "0" and "10" ends at each end, 0 points means no pain, and 10 points represent the most severe pain that is unbearable.
次要结局
- Concentration of serum cortisol(the day before surgery; When entering the operating room; 10minutes after peeling; 5 minutes after the operation; The first day after surgery)
- Postoperative nausea and vomiting(The day before surgery; After the operation 24hours, 48hours)
- Early postoperative recovery of quality(The day before surgery; After the operation 24hours, 48hours)
- Exhaust and bowel movements(After the operation 24hours, 48hours)
- Concentration of serum interleukin-6(the day before surgery; When entering the operating room; 10minutes after peeling; 5 minutes after the operation; The first day after surgery)
- Concentration of serum C-reactive protein(the day before surgery; When entering the operating room; 10minutes after peeling; 5 minutes after the operation; The first day after surgery)
研究者
Wang wanxia
Principal Investigator
Yangzhou University