The effect of ketamine and dexmedetomidine on preoperative sedation and intraoperative bleeding and analgesia during recovery
Phase 3
- Conditions
- Evaluation of the effect of ketamine or dexmedetomidine on placebo for preoperative relaxation& Intraoperative hemorrhage and postoperative analgesia in patients undergoing adenotonsillectomy.
- Registration Number
- IRCT20100518003954N9
- Lead Sponsor
- Hamedan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 3
Inclusion Criteria
Children undergoing adenotonsillectomy surgery who do not have concomitant disease.
Exclusion Criteria
Drug sensitivity to ketamine or dexmedothymidine
Mental retardation
ADHD
Psychiatric drug use
History of heart, kidney, liver disease
Any pathological problems in the nose
Patients who return to the operating room due to postoperative bleeding
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Relaxation before intranasal injection of ketamine or dexmedetomidine in adenotonsillectomy. Timepoint: Evaluation of sedation before adenotonsillectomy in children receiving intranasal ketamine or dexmedetomidine versus placebo 15 and 30 minutes after drug administration. Method of measurement: Questionnaire according to clinical criteria.
- Secondary Outcome Measures
Name Time Method Evaluation of the effect of medication on intraoperative bleeding. Timepoint: At the end of surgery. Method of measurement: Calculation of bleeding inside the suction bottle and bleeding medical gases.;Evaluation of the effect of medication on postoperative pain and restlessness. Timepoint: Evaluation of patient pain and restlessness at 15, 30, 45 and 60 minutes after surgery in recovery. Method of measurement: Using the standard questionnaire: Children's Hospital of Eastern Ontario pain score and Pediatric Anesthesia Emergency Delirium (PAED) scal.