analgesic effect of intra-nasal ketamine

Phase 2

• Conditions: fracture of upper limb , fracture of lower limb.; Fracture of upper limb, level unspecified,Fracture of lower limb, level unspecified; T10,T12

• Registration Number: IRCT2015061722777N1
• Lead Sponsor: Arak University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 154

Inclusion Criteria

Patients with isolated trauma with fracture in the upper or lower extremities; aged between 16 and 60 years old; with Visual Analogue Scale pain score of more than 50 mm.
Exclusion criteria: Patient’s refusal to participate in the study; having an underlying medical condition such as migraine, cardiac ischemia, schizophrenia, addiction, history of allergy to opiates or ketamine, head trauma or loss of consciousness; blood pressure of more than 180/100; vital signs Instability before and during the study; pregnancy; nasal deformity or injury which prevents nasal medication administration; any inability to express their pain during the study; consumption of high doses of analgesics within the last 4 hours, such as tramadol, methadone and opiates; presence of other trauma.

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Pain reduction. Timepoint: in 0, 5 ,10 , 20 and 30 min. Method of measurement: Vas Score.

Secondary Outcome Measures

Name	Time	Method
Dizziness, nausea, pain, burning throat, amnesia, headache, pain or burning sensation. Timepoint: in 5 , 10 , 20 , 30 min. Method of measurement: physical examination.