pright magnetic resonance imaging for evaluation of lateral recess stenosis of the lumbar spine

• Conditions: M48.06; M54.3; Sciatica

• Registration Number: DRKS00013292
• Lead Sponsor: niversitätsklinikum Freiburg

Brief Summary

pright MRI, as a non-invasive diagnostic modality, is capable of demonstrating an incr ease in lateral recess stenosis under axial loading. However, the reduced image quality of the applied 0.25 Tesla scanner, the limits of the measurement accuracy as well as the restrictedly investig able patient collective have to be taken into account in a limiting manner. The extent to which upright MRI can support future surgical indications as a complementary imaging modality remains to be investigated.

Detailed Description

Not available

Study Timeline

• Study Start: 2017-11-10
• Study Completion: 2021-04-19
• Results First Posted: 2022-12-08
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 10

Inclusion Criteria

Leg pain, aggravating under axial loading (in upright position e.g. standing, walking)
- inconclusive standard MRI in supine position and therefor indication for conventional myelographie

Exclusion Criteria

Absent indication for conventional myelography;
S.p. lumbar spondylodesis; Contraindication for MRI: (cardiac pace maker, defibrillator, LVAD-device cochlea implant, ferromagnetic material); BMI>30kg/m2; claustrophobia

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
A) Extent of lateral recess stenosis<br>Measurement of the lateral recess in axial MRI slices in anterior-posterior direction. Soft tissue or bony edges are defined as borders. Measurements in the relevant nerve root level are performed in all slices depicting the affected nerve root in the lateral recess. Measurements are performed in the standard MRI in supine position, in the upright MRI and in the myelography respectively.<br>B) Quantitative evaluation of contrast and signal to noise ratio in the Upright MRI. Qualitative evaluation of image quality using a 4-grade scale. Image evaluation is performed by two experienced neuroradiologists.