Diagnosis of bacteremia in suspected sepsis using functionalized iron oxide nanoparticles

Not Applicable

• Conditions: A41.9; Sepsis, unspecified

• Registration Number: DRKS00032571
• Lead Sponsor: niversitätsklinikum Erlangen

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2023-09-11
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Enrolling by invitation
• Sex: All
• Target Recruitment: 500

Inclusion Criteria

Adult male or female patients who are capable of giving consent

Exclusion Criteria

- Patients who refuse to give consent to sample collection or are incapable of giving consent.
- Patients in whom blood cultures cannot be taken (e.g. due to unfavourable vascular conditions).

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Time to pathogen identification using nanoparticle-based diagnostics versus conventional blood culture diagnostics in patients with suspected sepsis or severe infection.

Secondary Outcome Measures

Name	Time	Method
- Species identification of cultivated germs by MALDI-TOF analysis. <br>- Time from blood collection to detection, identification and resistance testing<br>- Categorical results and minimum inhibitory concentrations of resistance testing