Performance of New Diagnostic Methods in Older Adults With Pneumonia
Recruiting
- Conditions
- Pneumonia
- Registration Number
- NCT06092008
- Lead Sponsor
- Ohio State University
- Brief Summary
Create a clinical diagnostic pathway for older ED adults with pneumonia and its subgroups (bacterial, viral, and co-infection) and determine whether novel biomarkers improve diagnostic accuracy. The investigators will conduct a prospective observational trial of 250 ED patients ≥65 years old with suspected pneumonia. The investigators will perform analyses overall and by subgroups, seeking common models to ease adoption.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 250
Inclusion Criteria
- Adults aged 65 and older presenting to the ED with suspected pneumonia defined as (1) either a physician order for CXR OR CT OR a chief complaint consistent with dyspnea; AND (2) physician suspicion of pneumonia prior to ED testing (score of 2-5 on Likert scale)
Exclusion Criteria
- inability to obtain consent from the patient or an LAR
- active cancer
- organ transplant
- immunosuppression
- trauma activation
- suicidal ideation
- incarceration
- antibiotics in the last 14 days
- a separate episode of lower respiratory illness in the last 30 days
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Pneumonia 3 years Presence or absence of pneumonia based on adjudicator review of chart. The goal of the study is to create a diagnostic pathway for pneumonia in older adult emergency department patients.
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
The Ohio State University
🇺🇸Columbus, Ohio, United States