NL-OMON52275
Not yet recruiting
Not Applicable
Multimodal Optical-imaging of Retinal manifestations of Alzheimer*s Disease - MORAD
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Alzheimer's Disease
- Sponsor
- Vrije Universiteit Medisch Centrum
- Enrollment
- 150
- Status
- Not yet recruiting
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Age \>\= 50 years
- •Mini Mental State Exam (MMSE) greater or equal to 17 (patients who are mentally
- •Available AD biomarker information
Exclusion Criteria
- •\- Pupil dilation inadequate or contraindicated
- •\- Presence of glaucoma, retinal vasculopathy (diabetic, hypertensive)
- •\- Presence of moderate / late\-stage age\-related macular degeneration
- •\- Media opacities (cataract) precluding good quality imaging
- •\- Refractive error outside the range \-6D to \+6D
- •\- Inability to obtain good quality images with the OCT(\-A), widefield fundus
- •photography and metabolic hyperspectral retinal camera
- •\- Ocular conditions including eye infection, eye inflammation, eye surgery
- •last 28 days or other acute eye conditions.
- •Presence of other neurodegenerative disease (i.e. other causes of dementia, MS,
Outcomes
Primary Outcomes
Not specified
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