Effect of helicobacter pylori eradication on regression of gastric precancerous lesion in 1st degree relatives of patients with gastric cancer
Phase 3
- Conditions
- Gasteric Cancer.Malignant neoplasm of stomach
- Registration Number
- IRCT138706131155N2
- Lead Sponsor
- Guilan Govermental Province
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 480
Inclusion Criteria
1st degree relatives of patients with gastric cancer (father , mother, sister and brother. son and doughter), aged 40-65 years old, with gastritis, dont limit to antrum, and precancerous lesions with helicobacter pylori infection, giving informed consent.
Exclusion criteria: cases of gastric cancer, peptic ulcer with endoscopic evidence, history of gasterctomy, chronic or serious medical diseases (renal failure, CHD, liver disease, etc )
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Eradication of helicobacter pylori. Timepoint: 6-8 weeks after treatment. Method of measurement: UBT.;Regression of precancerous lesions. Timepoint: one year after onset of treatment. Method of measurement: endoscopy and pathology.
- Secondary Outcome Measures
Name Time Method