Whole-body Vibration on Mucus Clearance, the Quality of Life, and Exercise Capacity for Patients With Chronic Obstructive Pulmonary Disease
- Conditions
- COPD
- Interventions
- Device: A vertical vibration platform PowerVibe Zen Pro 5900Device: HFCWO
- Registration Number
- NCT04952363
- Brief Summary
Although whole body vibration (WBV) is mainly designed to promote neuromuscular function, however, because of its vibration characteristics, whether it can provide additional effects on the sputum clearance for chronic obstructive pulmonary (COPD) disease patients, thereby improving the quality of life, and exercise capacity is still unknown.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 26
- Confirmed diagnosis of COPD at the outpatient thoracic medicine clinic
- Need HFCWO as judged by the doctor
- Acute COPD exacerbation within the previous 4 weeks,
- Contraindication for WBVT (e.g., artificial joint replacement, a history of deep vein thrombosis, or known aortic aneurysm)
- Inability to perform squatting exercises
- Acute disc disease
- Inability to complete the 6MWT
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description HFCWO+WBVT HFCWO Subjects received HFCWO+WBVT intervention twice a week for a period of 8 weeks HFCWO+WBVT A vertical vibration platform PowerVibe Zen Pro 5900 Subjects received HFCWO+WBVT intervention twice a week for a period of 8 weeks HFCWO only HFCWO Subjects received HFCWO intervention twice a week for a period of 8 weeks
- Primary Outcome Measures
Name Time Method chronic obstructive pulmonary disease assessment test (CAT) 8 weeks questionnaire of COPD symptoms, scores ranging from 0 to 40, higher scores indicating more severe impact of COPD on their life
FVC(% pred) 8 weeks percentage of predicted FVC value (% pred)
1 min STST 8 weeks the number of repetitions performed in the 1-min sit-to-stand test (rep.)
FVC 8 weeks forced vital capacity tested in pulmonary function test (Liters)
Distance-Saturation Product (DSP) 8 weeks the product of distance walked and lowest oxygen saturation during the 6-min walk test (m%)
FEV1/FVC 8 weeks forced expiratory volume in 1 second divided by forced vital capacity in pulmonary function test (%)
Predicted distance 8 weeks percentage of the predicted 6 minute walk test distance (%pred)
5-rep STST 8 weeks the complete time for the 5-repetition sit-to-stand test (sec)
Muscle strength test2 8 weeks maximal force output for quadriceps muscle (lbs)
X-ray score 8 weeks the evaluation of the chest radiography based on the sputum impaction score, scores ranging from 0 to 18. A decrease in score represented an improvement in sputum in each area.
modified Medical Research Council (mMRC) 8 weeks questionnaire of dyspnea, scores ranging from 0 (low degree of dyspnea) to 4 (high degree of dyspnea)
Saint George Respiratory Questionnaire (SGRQ) 8 weeks questionnaire of overall health, daily life, and perceived well-being, scores ranging from 0 (no health impairment) to 100 (maximum health impairment)
FEV1 8 weeks forced expiratory volume in 1 second in pulmonary function test (Liters)
FEV1(% pred) 8 weeks percentage of predicted FEV1 value (% pred)
6 min walk distance 8 weeks the distance walked in 6 minutes (m)
Muscle strength test1 8 weeks Maximal force output for biceps femoris muscle (lbs)
Sputum self-assessment scale 8 weeks questionnaire of sputum volume, it contained three items (0-25 mL/d, 25-50 mL/d, and 50-100 mL/d) as a checklist
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Kaohsiung Medical University Hospital
🇨🇳Kaohsiung, Taiwan