The effect of protein with different doses on nitrogen balance

Phase 2

Recruiting

Conditions: Patients admitted to the intensive care unit.
Encounter for other specified special examinations
Z01.8

Registration Number: IRCT20170903036041N6

Lead Sponsor: Iran University of Medical Sciences

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Recruiting

Sex: All

Target Recruitment: 60

Inclusion Criteria

Age over 18 years
At least 11 days of hospitalization in the intensive care unit

Exclusion Criteria

Death or discharge before 11 days of hospitalization in the intensive care unit
Patients with liver, kidney and dialysis failure
Anuric, oliguric or diarrhea patients
Patients with high drain secretions
A glomerular filtration rate less than 50

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
itrogen balance. Timepoint: Urine 24 hours admission time, time to reach the protein target and the 11 day study. Method of measurement: Based on the measurement of urea concentration in urine.;Thickness of biceps brachii muscle. Timepoint: Beginning and day 11 of the study. Method of measurement: Sonography.

Secondary Outcome Measures

Name	Time	Method
Duration of use of mechanical ventilation. Timepoint: Duration of hospitalization. Method of measurement: Visit the patient/patients' files.;The duration of the patient's hospitalization in the intensive care unit. Timepoint: The total number of days the patient is in the ward. Method of measurement: Patients' files.;The number of positive cultures of nosocomial infection. Timepoint: The duration of the patient's hospitalization in the intensive care unit. Method of measurement: The number of positive culture results.;Mortality. Timepoint: 28 days after receiving interventions. Method of measurement: The discharge status of the patient as well as telephone follow-up 28 days after receiving the intervention.