MR-guided LITT therapy in patients with primary irresectable glioblastoma: a randomized pilot study
Phase 2
Completed
- Conditions
- brain cancerglioblastoma10029211
- Registration Number
- NL-OMON55122
- Lead Sponsor
- Radboud Universitair Medisch Centrum
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 15
Inclusion Criteria
- Informed consent, age >18-year-old
- Supratentorial localization
- Maximal volume <=70cc on post-contrast T1 MRI
- Safe trajectory/trajectories possible for ablation of at least 70% of the
tumour, avoiding eloquent structures or transgression of a ventricle or vessel.
- Karnofsky Performance Status (KPS) >= 70
Exclusion Criteria
- Contra-indication for general anaesthesia or MRI
- Lesion >70cc on post-contrast MRI on the day before intervention.
- Non-glioblastoma diagnosis as per frozen section analysis
- Pregnancy
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method