A clinical trial to study the effect of intraabdominal pressure guided positive end expiratory pressure on driving pressure in paediatric laparoscopic surgery
Not Applicable
- Conditions
- Health Condition 1: O- Medical and Surgical
- Registration Number
- CTRI/2022/03/041242
- Lead Sponsor
- Rakesh Kumar
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1.Parents willing to give consent for inclusion in study
2. Children age more than one year and less than 12 years(1-12yrs).
3. American society of anaesthesiology(ASA) physical status less than IV.
4. Elective laparoscopic surgery of more than one hour of pneumoperitoneum and in lateral position
Exclusion Criteria
1.Parental refusal to participate in the study.
2.Children with known severe lung disease.
3.Children with a history of severe lung infection having post infection sequelae in preoperative chest x-ray.
4.Children with known deformity of chest wall or thoracic spine.
5.Children with pre-existing significant cardiac, renal or hepatic diseases.
6. Children with history of previous thoracic surgery.
7.Children with BMI > 30 kg/m2
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Change in driving pressure in both groups at the end of pneumoperitonium.Timepoint: Change in driving pressure in the both groups at the end of pneumoperitoneum
- Secondary Outcome Measures
Name Time Method 1.Peak airway pressure , Plateau pressure and mean airway pressure at the end of pneumoperitonium and 15 minutes interval during pneumoperitonium. <br/ ><br>2.static lung compliance at the end of pneumoperitonium and 15 minutes interval during pneumoperitonium. <br/ ><br>3.lung ultrasound score after induction and one hour after extubation. <br/ ><br>4.PaO2/FiO2 ratio, alveolar-arterial oxygen gradient and PaCO2 and ETCO2 difference <br/ ><br>5. Room air oxygen saturation <br/ ><br>6. Incidence of intraoperative hypotension and Bradycardia <br/ ><br>Timepoint: 1 at end of pneumoperitoneum <br/ ><br>2 at end of pneumoperitoneum <br/ ><br>3 after induction and 1 hour post extubation <br/ ><br>4after pneumoperitoneum and pneumoperitoneum deflation <br/ ><br>5 post-op day 1or3 or at time of discharge whichever earlier <br/ ><br>6. Intraoperative