Sevoflurane, Laryngeal Mask Airway and Single-dose Dexmedetomidine: A Better Choice for Patients Undergoing Endovascular Coil Embolization
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 入组人数
- 64
- 试验地点
- 1
- 主要终点
- Observing the recovery characteristics of patients who were scheduled to undergo endovascular coil embolization.
研究概览
简要总结
The investigators designed a double-blind, randomized placebo-controlled study to determine the effects of dexmedetomidine on the recovery characteristics of patients who were scheduled to undergo endovascular coil embolization.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •18-65 years old ASA I or ASA II patients undergoing ECE treatment for intracranial aneurysms were included.
排除标准
- •Patients were excluded based on the following parameters: older than 65 yrs, a history of mental illness, recent use of sedatives or analgesics and with sensation.
研究组 & 干预措施
sevoflurane and 0.5 μg/kg dexmedetomidine
After induction of general anesthesia, Group DEX1 received a single dexmedetomidine dose of 0.5 μg/kg over 10 minutes.
干预措施: sevoflurane and 0.5 μg/kg dexmedetomidine (Drug)
sevoflurane and 1 μg/kg dexmedetomidine
After induction of general anesthesia, Group DEX2 received a single dexmedetomidine dose of 1 μg/kg over 10 minutes.
干预措施: sevoflurane and 1 μg/kg dexmedetomidine (Drug)
结局指标
主要结局
Observing the recovery characteristics of patients who were scheduled to undergo endovascular coil embolization.
时间窗: At the end of the operation and 24 hours later
The time from termination of the general anesthetic to the time that the patient's eyes opened. Anesthesiologists collected information on emergence agitation, postoperative nausea and vomiting for 24 hours after the surgery.
次要结局
未报告次要终点
研究者
Wen-fei Tan
Associate professor
China Medical University, China