Effect of Pressure Support Ventilation and Neurally Adjusted Ventilatory Assist (NAVA) in Chronic Obstructive Pulmonary Disease (COPD) Patients

Not Applicable

Completed

• Conditions: Chronic Obstructive Pulmonary Disease
• Interventions: Procedure: PSV and NAVA

• Registration Number: NCT00568100
• Lead Sponsor: Policlinico Hospital

Brief Summary

The investigators' aim is to study the effect of pressure support ventilation at two levels of PEEP and Pressure Support versus neurally adjusted ventilatory assist (NAVA) in COPD patients.

Detailed Description

In this study, two levels of pressure support and PEEP during pressure support ventilation are compared with neurally adjusted ventilatory assist (NAVA) in COPD patients by measuring respiratory mechanics, intrinsic PEEP, work of breathing and patient's level of comfort.

Study Timeline

• Study First Submitted: 2007-12-04
• Study First Submitted QC: 2007-12-04
• Study First Posted: 2007-12-05
• Study Start: 2010-04
• Primary Completion: 2014-11
• Study Completion: 2014-11
• Status Verified: 2015-04
• Last Update Submitted: 2015-04-27
• Last Update Posted: 2015-04-28

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 15

Inclusion Criteria

• Stable COPD patients during non invasive mechanical ventilation

Exclusion Criteria

• Haemodynamic instability
• Coma

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
1	PSV and NAVA	COPD patients

Primary Outcome Measures

Name	Time	Method
Respiratory mechanics, gas exchange, work of breathing	5 minutes

Secondary Outcome Measures

Name	Time	Method
Comfort of breathing	5 minutes

Trial Locations

Locations (1)

Policlinico Hospital; 🇮🇹 Milano, Italy