The comparison of treatment with dienogest and contraceptive oral pills on the improvement of pain, and quality of life in surgery patients with advanced endometriosis
Phase 1
- Conditions
- Advanced endometriosis.Endometriosis
- Registration Number
- IRCT20191011045063N1
- Lead Sponsor
- Iran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 108
Inclusion Criteria
Early diagnosis of endometriosis and chronic pelvic pain associated with endometriosis
Patients with advanced endometriosis who underwent surgery
Age 18 - 45 years
Body mass index (BMI) 18.5 – 29.9 kg/m2;
No gynecological malignancy
No contraindications to OCP or dienogest
No plans of pregnancy in the near
No underlying diseases
Exclusion Criteria
Personal dissatisfaction for inclusion in the study
Patients whose pelvic pain originates from other organs
Use of gonadotropins or other hormones three months before surgery
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Pain. Timepoint: Before surgery, 3 and 6 months after surgery. Method of measurement: Pelvic pain and dyspareunia scores are evaluated using the Visual Analogue Scale (VAS) and dysuria and dyschezia using a three-point score questionnire by possible answers to the items were yes”, no”, and a little”.
- Secondary Outcome Measures
Name Time Method Quality of life. Timepoint: Before surgery, 3 and 6 months after surgery. Method of measurement: Quality of life was measured using WHOQOL-BREF.;Edverse effects of the treatment. Timepoint: 3 and 6 months after surgery. Method of measurement: Questionnaire.;Pain recurrence. Timepoint: 6 months after surgery. Method of measurement: Questionnaire.