Cyclic administration of Dienogest for dysmenorrhea in adenomyosis
Phase 4
- Conditions
- Health Condition 1: N800- Endometriosis of uterus
- Registration Number
- CTRI/2024/02/062618
- Lead Sponsor
- Songklanagarind hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Applicable
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1.Adenomyosis is diagnosed by ultrasound
2.Dysmenorrhea with visual analog scale more than 3
3.Woman with regular frequency of menstruation 24-38 days for 3 cycles
4.No pregnancy desire during the treatment and trial period
5.No co-existing endometrioma or myoma or current PID by pelvic examination and ultrasonography
Exclusion Criteria
1.Contraindication of dienogest
2.Previous hormonal treatment within 3 months or current use
3.History or suspicious of gynecologic malignancy or hormonal responsive tumor
4.Currently breastfeeding
5.Current use of drugs with interaction to cytochrome P450
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To evaluate the change in visual analog scale (VAS) of dysmenorrhea during treatment women diagnosed with adenomyosis by cyclic regimen of dienogestTimepoint: 3 months
- Secondary Outcome Measures
Name Time Method To evaluate adverse effect of cyclic regimen of dienogest.Timepoint: 3 months;To evaluate patterns and amount of uterine bleeding during treatment with cyclic regimen of dienogest.Timepoint: 3 months