Evaluation of the skin firmness and elasticity

Phase 4

• Conditions: Sagging skin; R23.4

• Registration Number: RBR-82y4dz
• Lead Sponsor: KOSMOSCIENCE CIENCIA E TECNOLOGIA COSM IMP EXP LTDA

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2015-02-18
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Data analysis completed
• Sex: Female
• Target Recruitment: Not specified

Inclusion Criteria

Female volunteers, aged between 18 and 60 years, with skin phototype I to IV and intact skin in the region of the test; signs of sagging in the area evaluated; good physical condition and mental health; agreement not to use any topical products on the arms between the 48 h period before the day of the beginning of the study until the end of this; signing the Informed Consent Form ICF.

Exclusion Criteria

Skin marks in the experimental area that interfere with evaluation of possible skin reactions, pigmentation disorders , vascular malformations , scars , increased hairiness , freckles and warts aplenty, sunburn ; dermatoses active local or widespread , that may interfere with results of the study .
Pregnant or lactating ; a history of allergic reactions , irritation or discomfort to intense feelings of topical products : cosmetics or medicines ; history of atopy ; intense sun exposure or tanning session up to 15 days before the initial evaluation or during the study prediction of intense sun exposure during the study ; body dermatological aesthetic treatment or up to 03 weeks before selection, such as : mesotherapy , carboxiterapia and body peels.
Use of the following medications topical or systemic use : immunosuppressants , antihistamines , NSAIDs and corticosteroids to 2 weeks prior to or during the study period ; treatment with Vitamin A acid and / or its derivatives orally or topically for 1 month prior to study initiation .
Be participating in another study or have participated in another study with cosmetic until a week before the study inclusion ; ingestion of nutritional supplements that can influence the results of the study ; any condition which , in the opinion of the investigator , may compromise the evaluation of the study .

Study & Design

• Study Type: Intervention
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Increase in the skin elasticity and firmes, determined through cutometria in baseline and after 28 days of home use of the Sweet Almond Oil or Macadamia Oil or Grapessed Oil ;Sweet Almond Oil no conferred increased significantly of the firmness in skin, but increased significantly elasticity skin by 2.5% after 28 <br>days of use. <br>Macadamia Oil no conferred significantly increased of the firmness and elasticity of the skin after 28 days of use. <br>GrapeSeed Oil conferred significantly increased of 6.8% and 1.8% of the firmness and elasticity of the skin, respectively, after 28 days of use.

Secondary Outcome Measures

Name	Time	Method
not applicable