Lipid Profile in Diabetic and Non Diabetic CKD Patients

Recruiting

• Conditions: Chronic Kidney Disease Patients

• Registration Number: NCT06802978
• Lead Sponsor: Sohag University

Brief Summary

The goal of this observational study is to compare blood lipid (fat) levels in participants with chronic kidney disease (CKD) with diabetes and without diabetes and who over 20 years old.

The main question this study aims to answer is:

Does having diabetes make fat problems worse in people with chronic kidney disease (CKD), or is there no connection between them?

Researchers will compare the blood lipid (fat) levels in people with chronic kidney disease (CKD) who have diabetes and those without diabetes to see if having diabetes makes lipid problems worse in CKD patients, or if there is no connection between diabetes and changes in lipid levels.

Participants will need to fast for 10 hours before undergoing this test. This means not eating any food or drinking anything except water.

Samples will be taken and sent to laboratory immediately.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2025-01-26
• Study First Submitted QC: 2025-01-26
• Study First Posted: 2025-01-31
• Study Start: 2025-02-01
• Status Verified: 2025-04
• Last Update Submitted: 2025-04-17
• Last Update Posted: 2025-04-23
• Primary Completion: 2025-05
• Study Completion: 2025-06

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 200

Inclusion Criteria

• Patients of chronic kidney disease (CKD) presenting to the Sohag University Hospital
• Patients aged above 20 years of age.
• All patients who have given consent for enrolling into the study.

Exclusion Criteria

• Patients aged 20 years of age or below.
• Patients on lipid-lowering drugs.
• Kidney transplanted patients.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Assessment and comparison of the lipid profile between diabetic and non-diabetic chronic kidney disease patients using the colorimetric method on a fully automated biochemistry analyser.	February 2025 to May 2025.	Lipid profile were assessed in samples of chronic kidney disease patients , both with diabetes and without diabetes, after obtaining informed consent to compare lipid profile between these two groups.; Overnight fasting samples were taken and sent to the laboratory immediately. Serum was separated within 2 hours after collection to prevent artifactual changes in the concentration of HDL. After clot retraction occurred, the serum was transferred to a centrifuge tube and centrifuged at 2000 rpm for 5 minutes. The clear supernatant serum was then pipetted out using dry piston pipettes with disposable tips and stored in dry thin walled vials at 4°C. The samples were analyzed on the same day.; The following parameters were analyzed using the colorimetric method on a fully automated biochemistry analyser.; 1. Serum Cholesterol; 2. Serum Triglyceride; 3. Serum HDL (high-density lipoprotein); 4. Serum LDL ( low-density lipoprotein); 5. Serum VLDL (very low-density lipoprotein)

Trial Locations

Locations (1)

Department of Internal Medicine , Sohag University Hospital.; 🇪🇬 Sohag, Egypt