Bioavailability of Pea Protein in Young and Old Volunteers
Not Applicable
Completed
- Conditions
- Healthy Male Volunteers
- Interventions
- Dietary Supplement: Pea protein (NUTRALYS ® S85 plus) in waterDietary Supplement: Pea protein (NUTRALYS ® S85 plus) within mealDietary Supplement: Whey protein in waterDietary Supplement: Whey protein within meal
- Registration Number
- NCT06381869
- Lead Sponsor
- Roquette Freres
- Brief Summary
The aim of this study done in healthy, non-malnourished young and elderly subjects, is to measure the bioavailability of protein intake and the variation of metabolic markers following consumption of pea protein " NUTRALYS ® S85 plus" or a reference protein brought in water either alone or at the end of a standardized meal.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Male
- Target Recruitment
- 30
Inclusion Criteria
- Adult male volunteers, aged over 65 or under 30
- Body mass index (weight in kg/ height² in m²) between 22 and 28 kg/m²,
- Subjects considered to be healthy by the principal investigator doctor according to the interview, medical and clinical examination,
- Biological assessment considered compatible with participation in the study,
- Persons able to sign the informed consent,
- Persons affiliated to social security scheme.
Exclusion Criteria
- Pathologies or treatments not compatible with the study
- Food allergy or a contraindication to the consumption of the products tested
- Subject in a situation which, in the opinion of the investigator, could interfere with their optimal participation in the study or constitute a particular risk for the subject,
- Subject with a particular diet (vegetarians, vegans, nutritional supplements, etc.),
- Subject weighing < 55 kg,
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- CROSSOVER
- Arm && Interventions
Group Intervention Description Young volunteers Pea protein (NUTRALYS ® S85 plus) in water Volunteers under 30 years old Elderly volunteers Pea protein (NUTRALYS ® S85 plus) within meal Volunteers over 65 years old. Young volunteers Whey protein in water Volunteers under 30 years old Young volunteers Pea protein (NUTRALYS ® S85 plus) within meal Volunteers under 30 years old Young volunteers Whey protein within meal Volunteers under 30 years old Elderly volunteers Pea protein (NUTRALYS ® S85 plus) in water Volunteers over 65 years old. Elderly volunteers Whey protein in water Volunteers over 65 years old. Elderly volunteers Whey protein within meal Volunteers over 65 years old.
- Primary Outcome Measures
Name Time Method Leucine blood concentration 0 minute before eating the test meals, then regularly until 360 minutes after ingestion.
- Secondary Outcome Measures
Name Time Method Essential amino acids blood concentration (µmol/L) 0 minute before eating the test meals, then regularly until 360 minutes after ingestion. Non essential amino acid blood concentration (µmol/L) 0 minute before eating the test meals, then regularly until 360 minutes after ingestion. Blood glucose concentration (g/L) 0 minute before eating the test meals, then regularly until 360 minutes after ingestion. Blood insulin concentration (μIU/ml) 0 minute before eating the test meals, then regularly until 360 minutes after ingestion. Blood lipid profile (glycerol concentration in mg/l and non-esterified fatty acids concentration in mg/l) 0 minute before eating the test meals, then regularly until 360 minutes after ingestion. Blood inflammatory profile (TNF-α blood concentration in pg/ml and IL-6 blood concentration in pg/ml) 0 minute before eating the test meals, then regularly until 360 minutes after ingestion.
Trial Locations
- Locations (1)
Unité d'Exploration en Nutrition Centre de Recherche en Nutrition Humaine d'Auvergne
🇫🇷Clermont-Ferrand, France