The Effect of RF Genicular Nerve Block Applied in the Preoperative Period on Fast-track Total Knee Arthroplasty
- Conditions
- Knee OsteoarthritisKnee Pain Chronic
- Interventions
- Procedure: Genicular nerve Radiofrequency Ablation block
- Registration Number
- NCT06239649
- Lead Sponsor
- Pamukkale University
- Brief Summary
In our study, investigators plan to compare the preoperative RF and genicular nerve ablation approach in patients who underwent TKA(Total Knee Arthroplasty) using the Fast-Track protocol in terms of meeting postoperative pain, function and early discharge criteria.
- Detailed Description
One of the most important components of surgery using Fast-Track is the application of effective and well-monitored pain treatment. Post-surgical pain negatively affects the patient's early mobilization. Reduction in pain after TKA(Total Knee Arthroplasty) may not only increase short-term functional results but also increase the patient's overall satisfaction.
Genicular Nerve Radiofrequency Ablation (GNRFA) is a non-surgical treatment increasingly used in patients with advanced knee osteoarthritis. Previous studies have shown this to be an effective and safe method to reduce pain and improve functionality in this patient population.
Neurolysis of genicular nerves with radiofrequency (RF) may be useful to relieve pain and improve both function and quality of life in patients with post-TKA pain.
Investigators thought that reducing the pain of patients who underwent TKA with Fast-track in the postoperative period would contribute to early mobilization and therefore rapid functional recovery. As a result of previous studies, investigators know that genicular nerve neurolysis with RF Ablation in the preoperative period provides a reduction in postoperative pain.
Investigators routinely apply TKA applications in clinic with Fast-Track. In investigators hospital's algology outpatient clinic, genicular nerve RF ablation is routinely performed under USG or fluoroscopy guidance. In investigators study, investigators plan to compare the preoperative RF and genicular nerve ablation approach in patients who underwent TKA using the Fast-Track protocol in terms of meeting postoperative pain, function and early discharge criteria
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 60
- Being between the ages of 40 and 85,
- Being able to understand verbal and written information given in Turkish,
- Being able to speak and understand Turkish,
- Being subjected to unilateral TKA surgery due to the diagnosis of Primary Knee osteoarthritis
- Patients planned for revision knee prosthesis surgery,
- Patients previously diagnosed with psychiatric disorders,
- Patients who have undergone major surgery on the extremity where TKA will be applied,
- Patients with comorbid diseases such as rheumatoid arthritis or cancer,
- Patients with a score above 3 according to the American Society of Anesthesiologists (ASA) scoring,
- Patients with neurological diseases that cause functional disability,
- Patients with flexion limitation of more than 45 degrees and extension limitation of more than 20 degrees,
- Patients who have to use hypnotic or anxiolytic drugs regularly,
- Patients with alcohol or drug addiction,
- Patients with bleeding disorders
- Patients with uncontrolled diabetes
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description TKA with radiofrequency ablation genicular nerve block Genicular nerve Radiofrequency Ablation block TKA with radiofrequency ablation genicular nerve block
- Primary Outcome Measures
Name Time Method Knee Range of Motion preoperative Baseline (preoperatively) Digital goniometer used to assess knee range of motion
Performance-based activity limitations-preoperative 2 at postoperative twelfth week 30-sec chair-stand test and stair-climb test are used
Pain preoperative Baseline (preoperatively) Visual Analog Scale used to assess pain
Knee Range of Motion postoperative 2 at postoperative twelfth week Digital goniometer used to assess knee range of motion
Quadriceps muscle strength postoperative 2 at postoperative twelfth week Quadriceps muscle strength is measured (unit=newton(N)) with hand-held dynamometer
Quality of life-preoperative 2 at postoperative twelfth week Short Form-36 (SF-36) is used
Length of hospital stay through study completion, an average of 1 year Length of hospital stay is measured beginning from the hospitalization of the patient and ending at discharge of the patients (unit-hours)
Knee Range of Motion postoperative 1 at postoperative sixth week Digital goniometer used to assess knee range of motion
Quadriceps muscle strength postoperative 1 at postoperative sixth weeks Quadriceps muscle strength is measured (unit=newton(N)) with hand-held dynamometer
Patient-reported activity limitations preoperative 2 at postoperative twelfth week The Western Ontario and McMaster Universities Arthritis Index and Knee injury and Osteoarthritis Outcome Score are used
Performance-based activity limitations-preoperative Baseline (preoperatively) 30-sec chair-stand test and stair-climb test are used
Performance-based activity limitations-preoperative 1 at postoperative sixth weeks 30-sec chair-stand test and stair-climb test are used
Quality of life-preoperative Baseline (preoperatively) Short Form-36 (SF-36) is used
Pain postoperative 1 at postoperative sixth weeks Visual Analog Scale used to assess pain
Pain postoperative 2 at postoperative twelfth weeks Visual Analog Scale used to assess pain
Quadriceps muscle strength preoperative Baseline (preoperatively) Quadriceps muscle strength is measured (unit=newton(N)) with hand-held dynamometer
Patient-reported activity limitations preoperative Baseline (preoperatively) The Western Ontario and McMaster Universities Arthritis Index and Knee injury and Osteoarthritis Outcome Score are used
Patient-reported activity limitations preoperative 1 at postoperative sixth weeks The Western Ontario and McMaster Universities Arthritis Index and Knee injury and Osteoarthritis Outcome Score are used
Quality of life-preoperative 1 at postoperative sixth weeks Short Form-36 (SF-36) is used
- Secondary Outcome Measures
Name Time Method Length of operation time the surgery Length of operation time is measured in minutes during the surgery
Amount of blood loss through study completion, an average of 1 year Amount of blood loss is measured from the suction drainage (unit-milliliters)
postoperative component alignments through study completion, an average of 1 year Long leg radiographs of the patients are evaluated postoperatively by using a digital orthopedic templating software-Materialise OrthoView (OrthoView version 7, Materialise HQ, Technologielaan 15 3001 Leuven, Belgium).
Trial Locations
- Locations (1)
Pamukkale University
🇹🇷Denizli, Pamukkale, Turkey