Quantification of Daily Physical Activity After an Intra-articular Corticosteroid Injection in Patients With Knee Osteoarthritis
Overview
- Phase
- Phase 4
- Intervention
- Corticosteroids injection
- Conditions
- Knee Osteoarthritis
- Sponsor
- Laval University
- Enrollment
- 14
- Locations
- 1
- Primary Endpoint
- Change in Knee pain
- Status
- Completed
- Last Updated
- 12 years ago
Overview
Brief Summary
The objective of this study was to objectively measure daily physical activity and spatiotemporal gait pattern, as well as improvements in self reported symptoms and quality of life, before and six weeks after an intra-articular corticosteroids injection in patients suffering from knee osteoarthritis. Fourteen patients with unilateral knee osteoarthritis were recruited. The intra-articular corticosteroid injection was given at the end of the second week. Physical activity was objectively measured by an accelerometer worn by the participants for eight weeks. In addition, the Western Ontario and McMaster Universities Arthritis Index (WOMAC), the Medical Outcome Study Short Form-36 (MOS-SF36) and gait trials were completed every two weeks to assess symptoms, quality of life and spatiotemporal parameters of gait.
Investigators
Philippe Corbeil
Professor
Laval University
Eligibility Criteria
Inclusion Criteria
- •50 years old or more
- •Medial knee osteoarthritis (Kellgren \& Lawrence Grade I to III)
Exclusion Criteria
- •Intra-articular injection during the last six months
- •Isolated femoro-patellar arthritis
- •Rheumatoid arthritis
- •Knee instability
- •Spinal stenosis
- •Lower limb fracture over the last year
- •Lower limb surgery in the last three months
Arms & Interventions
Injection
Corticosteroids injection
Intervention: Corticosteroids injection
Outcomes
Primary Outcomes
Change in Knee pain
Time Frame: Change from Baseline at 2, 4 and 6 weeks
Change in physical activity
Time Frame: Change from baseline at 2, 4 and 6 weeks
Secondary Outcomes
- Change in function and quality of life(Change from baseline at 2, 4 and 6 weeks)
- Change in Spatiotemporal gait parameters(Change from Baseline at 2, 4 and 6 weeks)