Daily Activity Quantification and Gait Pattern Analysis Before and After Intra-articular Injection of Viscosupplement Among Hip Osteoarthritis Patients
Overview
- Phase
- Phase 4
- Intervention
- Hyaluronan
- Conditions
- Hip Osteoarthritis
- Sponsor
- Laval University
- Enrollment
- 38
- Locations
- 1
- Primary Endpoint
- Change in hip flexion-extension range of motion
- Status
- Completed
- Last Updated
- 7 years ago
Overview
Brief Summary
The objective of this study is to assess the changes in daily physical activity and gait pattern, following a viscosupplement injection among a population who is suffering from hip osteoarthritis. A kinetic and kinematic gait analysis, an Actigraph activity monitor, a functional Timed-Stair-Test and two questionnaires (Medical Outcome Study Short-Form36 (MOS-SF36), Hip disability and Osteoarthritis Outcome Score (HOOS)) about how the pathology affects the quality of life, will be use.
Investigators
Philippe Corbeil
PhD
Laval University
Eligibility Criteria
Inclusion Criteria
- •From 45 years old to 65 years old
- •Clinically symptomatic moderate or severe hip osteoarthritis (Tönnis Grade II to III)
- •Capacity to keep steady upright position and walking during 15 minutes
- •Body mass index \< 40kg/m2
Exclusion Criteria
- •Bilateral hip osteoarthritis
- •No broken hip or leg during the last 12 months
- •Bone necrosis
- •Rheumatoid arthritis, articular chondrocalcinosis, metabolic bone disease, psoriasis, gout, active infection
- •Per os corticosteroid treatment
- •Corticosteroid injection \< 3 months
- •Viscosupplement injection \< 6 months
- •Hypersensitivity to hyaluronic acid products
- •Planed surgery during study duration
- •Physical or mental disability to fill in questionnaires and/or to participate to follow-up
Arms & Interventions
Hyaluronan
Hyaluronan acid Neovisc : one 6cc (viscosupplement) intra-articular injection
Intervention: Hyaluronan
Bupivacaine
one Marcain extra-capsular injection
Intervention: Bupivacaine
Outcomes
Primary Outcomes
Change in hip flexion-extension range of motion
Time Frame: Change from Baseline at 6 months
Subtraction between maximum and minimum flexion measured with motion capture system during gait
Change in daily physical activity
Time Frame: Change from Baseline at 6 months
Intensity and duration of the daily physical activity measured with pedometer
Secondary Outcomes
- Change in hip pain(change from Baseline at 6 months)
- Change in quality of life(Change from Baseline at 6 months)
- Change in walking cadence(Change from Baseline at 6 months)