Effect of Zinc Suplementation on Serum Hemosystein Level in Hemodialysis Patients

Not Applicable

Completed

• Conditions: End Stage Renal Failure
• Interventions: Drug: placebo; Drug: Zinc Supplement

• Registration Number: NCT01101217
• Lead Sponsor: Shiraz University of Medical Sciences

Brief Summary

The purpose of this study is to study the effect of zinc supplementation in end stage renal failure on hemocystein level.

Detailed Description

hemocystein increased in end stage renal failure and zinc involved in hemocystein metabolism thus zinc supplementation may be effective on hemocystein level.

Study Timeline

• Status Verified: 2009-01
• Study Start: 2009-02
• Study Completion: 2009-09
• Study First Submitted: 2010-04-08
• Study First Submitted QC: 2010-04-08
• Last Update Submitted: 2010-04-08
• Study First Posted: 2010-04-09
• Last Update Posted: 2010-04-09

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

• hemodialysis for 3 months
• older than 18 years old
• serum level of zinc less than 72.6 microgram/ l in men and less than 70 microgram/ l in female

Exclusion Criteria

• acute renal failre
• malabsorption
• history of steroid or cytotoxic consumption

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
placebo	placebo	placebo for 6 weeks
zinc	Zinc Supplement	zinc sulfate 220 mg per day orally for 6 weeks

Primary Outcome Measures

Name	Time	Method
decreased hemocystein level	6 months

Trial Locations

Locations (1)

Shiraz University Hemodialysis Center; 🇮🇷 Shiraz,, Fars, Iran, Islamic Republic of