Impaired sensory processing in Autism Spectrum Disorder: Towards better phenotyping and cellular models*

• Conditions: Autism ASD; 10012562

• Registration Number: NL-OMON48762
• Lead Sponsor: V

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 28 February 2024

Recruitment & Eligibility

• Status: Pending
• Sex: Not specified
• Target Recruitment: 240

Inclusion Criteria

Diagnosis of Autism Spectrum Disorder, parent or sibling of person with Autism
Spectrum Disorder or Control
Scoring extreme high or low (7th percentile) on the Sensory
Processing questionnaire.

Exclusion Criteria

Control Participants are excluded if
-they have an IQ score below 80), based on educational attainment (Mavo/VMBO or
higher);
-if they are younger than 20 or older than 55 years;
-if they have a diagnosis of autism, or score above the cutoff on the Autism
Quotient Questionnaire, Participants with autisem are excluded if they are
-not clinically diagnosed with autisme

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>1. Self-reported behavioural questionnaire on sensory processing<br /><br>2. Self-reported behavioural questionnaire on daily life functioning, such as<br /><br>clinical severity, social problems, educational attainment, and wellbeing<br /><br>3. Neuropsychological tasks on sensory processing<br /><br>4. Neurophysiological (i.e., EEG) parameters<br /><br>5. Polygenic Risk Scores<br /><br>6. Cellular assays</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>nvt</p><br>