Tramadol iv. : Influence of Dose and Dose Intervals on Therapeutic Accuracy and Side Effects When Used for Postoperative Pain Relief in Ambulatory Surgery
Phase 2
Completed
- Conditions
- Ambulatory Surgery
- Registration Number
- NCT00333346
- Lead Sponsor
- University Hospital, Ghent
- Brief Summary
The aim of this study is to compare the administration of 1 unit dose of 100 mg tramadol intravenously versus multiple smaller dosages of tramadol during the first 6 hours post-operatively and to investigate the time course and accuracy of pain relief versus the onset and duration of side-effects.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 200
Inclusion Criteria
- ASA I and II female or male patients
- Aged 18-70 years
- Scheduled for ambulatory surgery requiring postoperative pain medication.
Exclusion Criteria
- Weight less than 70% or more than 130% of ideal body weight
- Neurological disorder
- Recent use of psycho-active medication, including alcohol
- Patients suffering from chronic pain receiving pre-operative pain medication including NSAID's
- Use of chronic anti-emetic medication, use of chronic corticoid therapy
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Primary Outcome Measures
Name Time Method Time course of pain relief Accuracy of pain relief Onset of side-effects Duration of side-effects
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
University Hospital Ghent
🇧🇪Ghent, Belgium