Surgical decompression versus local steroid injection in carpal tunnel syndrome

Completed

• Conditions: Carpal tunnel syndrome; Nervous System Diseases

• Registration Number: ISRCTN26264638
• Lead Sponsor: niversity Hospital Puerta de Hierro Majadahonda (Spain)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2012-02-02
• Last Update Posted: 13 January 2015

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

1. At least 18 years old
2. Symptoms of CTS of at least 3 months? duration
3. Referred by their primary care physicians to a CTS unit specifically created for this study
4. A presumptive diagnosis of CTS, and had been unresponsive to a course of at least 2 weeks of non-steroidal anti-inflammatory drugs (NSAIDs) and splinting.
5. CTS confirmed by electrodiagnostic testing according to Kimura´s criteria.

Exclusion Criteria

1. Patients with wrists with thenar atrophy
2. Previous carpal tunnel release surgery, or local injection for CTS
3. Patients who are pregnant
4. Patients which have diabetes mellitus
5. Patients which have hypothyroidism
6. Patients which have inflammatory arthropathy
7. Patients which have polyneuropathy

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Percentage of wrists reaching at least a 20% reduction in the VAS score for nocturnal paresthesias at 3 months of follow up.

Secondary Outcome Measures

Name	Time	Method
Percentages of wrists with a 20% reduction in the VAS score for nocturnal paresthesias at 6 and 12 months, a 20% response for pain and functional impairment, as well as a 50% and a 70% response in nocturnal paresthesias, pain, and functional impairment.