Goal-directed versus restricted fluid management during major hepatic surgery; a double blind randomized controlled pilot trial

Completed

• Conditions: Fluid therapy during liver surgery; 10019815

• Registration Number: NL-OMON45945
• Lead Sponsor: Academisch Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2018-06-29
• Results First Posted: 2019-01-16
• Last Update Posted: 23 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 52

Inclusion Criteria

Adult patients, undergoing open liver resection and which are able to provide written informed consent

Exclusion Criteria

* Known Pregnancy
* Known allergies to colloid fluids or contrast
* Pre-operative severe kidney dysfunction (GFR < 30).
* Severe decreased liver function disorders (i.e. PTT, APTT > 1.5 of normal) and/or low albumin)
* Significant ischemic heart disease, heart failure or severe arrhythmias
* Laparoscopic liver resection
* Minor resection (such as wedge resections)
* If no resection is performed

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Intraoperative blood loss</p><br>