Conservative versus goal directed fluid management based on stroke volume variation for reducing length of ICU stay in elderly patients undergoing elective craniotomy

Phase 3

Completed

• Conditions: craniotomybrain tumorcerebral aneurysm; craniotomy; brain tumor; cerebral aneurysm; elderly patient; stroke volume variation; ICU stay

• Registration Number: TCTR20190812003
• Lead Sponsor: Ratchadapisek Sompoch Endowment Fund Chulalongkorn university

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2019-08-12
• Study Completion: 2022-03-28
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

1. Age 60-80 years
2. Scheduled for elective craniotomy
3. ASA 2-3
4. expected duration of surgery more than 2 hours

Exclusion Criteria

1. permanent cardiac arrhythmia
2. severe cardiac disease ie. LVEF< 30%, moderate to severe AR or AS
3. BMI > 35 kg/m2
4. patients who are receiving vasopressor therapy before surgery

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
length of ICU stay At the timepoint when the patient meet all discharge criteria Institutional ICU discharge protocol

Secondary Outcome Measures

Name	Time	Method
lactae level at the end of surgery laboratory