Meditative Neurofeedback for Depression

Not Applicable

Recruiting

• Conditions: Depression - Major Depressive Disorder; Depression Disorders

• Registration Number: NCT06675240
• Lead Sponsor: University of California, San Diego

Brief Summary

The goal of this open-label single-arm study is to test a meditative neurofeedback intervention for depressed mood.

Detailed Description

The goal of this open-label single-arm study is to test whether a 10-session meditative neurofeedback intervention significantly alleviates depressive symptons as well as improves secondary outcomes of rumination and mindfulness.

Study Timeline

• Study First Submitted: 2024-11-03
• Study First Submitted QC: 2024-11-03
• Study First Posted: 2024-11-05
• Study Start: 2024-11-15
• Status Verified: 2025-03
• Last Update Submitted: 2025-03-24
• Last Update Posted: 2025-03-25
• Primary Completion: 2025-11-15
• Study Completion: 2026-06-15

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 27

Inclusion Criteria

• moderate depression per PHQ9 symptom ratings

Exclusion Criteria

• active substance abuse/dependence
• psychotic disorders
• bipolar disorder
• displaying acutely suicidal behaviors

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Primary Outcome Measures

Name	Time	Method
PHQ9	8 weeks	Depression Symptoms on the Patient Health Questionnaire 9-item (PHQ9) scale, min 0 max 27 with lower scores representing better outcome

Secondary Outcome Measures

Name	Time	Method
MAAS	8 weeks	Mindfulness on the Mindful Attention Awareness Scale (MAAS), min 6 max 84 with higher scores representing better outcome
GAD7	8 weeks	Anxiety symptoms on the Generalized Anxiety Disorder 7-item (GAD7) scale, min 0 max 21 with lower scores representing better outcome
RRQ	8 weeks	Rumination on the Ruminative Response Questionnaire (RRQ) scale, min 22 max 88 with lower scores representing better outcome

Trial Locations

Locations (1)

University of California San Diego; 🇺🇸 La Jolla, California, United States