Efficacy of Methylene Blue Mediated Photodynamic Therapy for Primary Localized Cutaneous Amyloidosis Treatment in Asians

Not Applicable

• Conditions: Lichen Amyloidosis
• Interventions: Procedure: Methylene blue-mediated photodynamic therapy

• Registration Number: NCT03068208
• Lead Sponsor: Chulalongkorn University

Brief Summary

Efficacy of Methylene blue mediated Photodynamic therapy for primary localized cutaneous amyloidosis treatment in Asians, pilot study.

Detailed Description

Not available

Study Timeline

• Status Verified: 2017-02
• Study First Submitted: 2017-02-20
• Study First Submitted QC: 2017-02-26
• Last Update Submitted: 2017-02-26
• Study First Posted: 2017-03-01
• Last Update Posted: 2017-03-01
• Study Start: 2017-05-01
• Primary Completion: 2018-04-30
• Study Completion: 2018-06-30

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 15

Inclusion Criteria

• Patients, aged > 18 years old with lichen amyloidosis diagnosed by using clinical presentation and pathological findings.

Exclusion Criteria

• Those with systemic disease associated cutaneous amyloidosis
• Pregnancy or lactating woman
• Those who are allergic to urea, olive oil
• Those who are photosensitive to ultraviolet radiation
• Those who had been previously treated with any of which -medications, radiation, laser within 3 months and 1 month for topical therapy

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
MB-PDT	Methylene blue-mediated photodynamic therapy	-

Primary Outcome Measures

Name	Time	Method
Roughness evaluation by using visioscan	Change from baseline roughness at every 2 weeks up to 16 weeks	The improvement of roughness during the treatment

Trial Locations

Locations (1)

King Chulalongkorn Memorial Hospital; 🇹🇭 Bangkok, Thailand