Effects of modafinil, caffeine and methylphenidate on functional brain activity and cognitive performance in healthy volunteers: a randomized, placebo-controlled, double-blind fMRI study. - MKM

Charité Campus Charité Mitte0 个研究点目标入组 48 人开始时间: 2014年2月17日最近更新: 2024年8月19日

适应症

试验速览

暂无简介。

•- Known hypersensitivity to the study medication
•- All contraindications to the study medication: arrhythmia, hyperthyroidism , glaucoma , pheochromocytoma , congestive heart failure , diabetes mellitus, known liver and kidney dysfunction, vascular disease , angina, haemodynamically significant congenital heart disease , cardiomyopathy , myocardial infarction, channelopathies, arterial hypertension , cerebrovascular diseases , such as cerebral aneurysm , vascular abnormalities , including vasculitis and stroke.
•- Participation in other clinical trials during or within one month prior to this clinical trial
•- Medical or psychological circumstances that may endanger the proper conduct of the trial
•- Existing serious somatic diseases, even if they are not covered by the contraindications according to product information
•- Existing psychiatric disorders and psychiatric disorders in prehistory
•- Smoker or ex-smoker for less than 5 years
•- Regular caffeine consumption > 4 cups per day
•- Subjects with irregular day -night rhythm (eg shift workers )
•- Unwillingness to the storage and disclosure of pseudonymous data as part of the clinical trial
•- Accommodation in an institution by court or administrative order (according to AMG § 40 (1) 4 )
•- MR contraindications ( eg pacemakers , metallic or electronic implants , metallic splinters , tinnitus, surgical clips )

发起方

Charité Campus Charité Mitte