Effects of probiotics on liver function in chronic liver disease

Completed

• Conditions: Cirrhosis; Digestive System

• Registration Number: ISRCTN50009946
• Lead Sponsor: The Prince of Wales Hospital (Australia)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2009-11-11
• Last Update Posted: 13 January 2015

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

1. Patients aged between 18 and 70 years (either sex) with established cirrhosis
2. No antibiotic or lactulose therapy within 6 weeks
3. No prior use of probiotic therapy

Exclusion Criteria

1. Age under 18 years or over 70 years
2. Antibiotic or lactulose therapy within 6 weeks
3. Prior use of probiotic therapy
4. Hepatocellular carcinoma

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Markers of liver function, measured at day 7, day 28 and day 56.

Secondary Outcome Measures

Name	Time	Method
Tolerability, measured at day 7, day 28 and day 56.