Identification of biomarkers that correlate with clinical features and outcomes following concussio

Not Applicable

Completed

• Conditions: Concussion; Injuries and Accidents - Other injuries and accidents

• Registration Number: ACTRN12615000543583
• Lead Sponsor: The University of Western Australia

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2015-05-28
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

a.Patients between 14 and less than 50 years of age
b.Presenting to ED within 48 hours of head injury with symptoms that may be attributable to that injury
c.Cranial CT scan shows no intracranial injury, or CT was not performed

Age and sex matched control subjects will be recruited from healthy volunteers known to the researchers.

Exclusion Criteria

a.Glasgow Coma Scale (GCS) 13 or less at time of initial assessment.
b.Ward of state, prisoner, under mental health treatment order.
c.Deemed unlikely to comply with 28 day follow up e.g. homeless.
d.Head injury deemed to be entirely due to primary seizure.
e.Clinically unstable from other injury or other significant non-TBI injury.
f.Non English speaking.
g.Known pre-existing cognitive impairment, such as an intellectual disability.

Study & Design

• Study Type: Observational
• Study Design: Not specified