Correlation of Genetic Characteristics with Development of Specific Diseases in Patients with Familial Adenomatous Polyposis
Not Applicable
- Conditions
- Family Adenomatous Polyposis, Colorectal Neoplasms, Gene APC, Mutation, Phenotype, GenotypeC04.588.274G05.695G05.365.590G05.380
- Registration Number
- RBR-84qkkv
- Lead Sponsor
- Fundação Pio XII
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruitment completed
- Sex
- Not specified
- Target Recruitment
- Not specified
Inclusion Criteria
Carriers of Classical Familial Adenomatous Polyposis Syndrome. Carriers of pathogenic germline variants in the APC gene.
Exclusion Criteria
Familiar members tested to the mutation in the APC gene not carrying APC gene-related mutation.
Patients carrying the mutation in the APC gene who are not willing to undergo the protocol of screening tests for colonic and extra-colonic manifestations.
Study & Design
- Study Type
- Intervention
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method