Investigation into the Acute and Chronic Effects of Longvida Curcumin on Cognitive Function, Mood and Biomarkers of Health in an Elderly Population.

Phase 3

• Conditions: Inflamation; Cognitive function; Cerebral Blood Flow (fMRI); Oxidative stress; Mood, stress and fatigue; Mental Health - Studies of normal psychology, cognitive function and behaviour; Alternative and Complementary Medicine - Herbal remedies

• Registration Number: ACTRN12612001027808
• Lead Sponsor: Swinburne University of Technology, Centre for Human Psychopharmacology

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2012-09-24
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

1. Male or female.
2. Aged 65-80 years.
3. Willing and able to provide written informed consent.
4. Understands and is willing and able to comply with all study procedures.
5. Free from history of stroke, other neurological conditions (e.g. Parkinsons, epilepsy), depression, psychiatric disorders, low base line intellect, alcohol abuse past / present.
6. Cognitively healthy participants must be free from any form of cognitive impairment. For the cognitively declined particpants, participants must have objective memory impairment for age and education level.
7. Free from dementia.
8. English speaking.
9. Must have normal or corrected vision.
10. Free from other medical conditions which may affect ability to participate in the study
11. Participants taking part in study Stage Two must be right handed

Exclusion Criteria

1. Any significant concurrent illness including any auto-immune disorder, bleeding disorders, heart conditions, diabetes, glaucoma, high blood pressure or osteoporosis.
2. Any known or suspected food allergies
3. Smokers and users of recreational drugs (except alcohol and other food grade actives).
4. Have participated in any other study involving an investigational product in the last 4 weeks.
5. Taking any of the following: anti-coagulant drugs (Warfarin,Heparin, Plavix); anti-cholinergics or acetylcholinesterase inhibitors: bethanechol (Ureholine), donepezil (Aricept),
6. Taking steroid medications
7. Taking vitamins or herbal supplements regularly
8. Left-handed participants will be ineligible to take part in Stage Two

Study & Design

• Study Type: Interventional
• Study Design: Not specified