Correlation Between Preoperative Images of PPGL and Intraoperative Hemodynamics
- Conditions
- PheochromocytomaParaganglioma
- Registration Number
- NCT06669481
- Lead Sponsor
- Peking Union Medical College Hospital
- Brief Summary
This is a retrospective observational cohort study involving patients with suspected PPGLs who underwent 131I-MIBG scanning and surgical treatment between January 2020 and April 2023. The objective is to evaluate the correlation between MIBG imaging score and intraoperative hemodynamic fluctuations.
- Detailed Description
This is a retrospective observational cohort study involving patients with suspected PPGLs who underwent 131I-MIBG scanning and surgical treatment between January 2020 and April 2023. The objective is to evaluate the correlation between MIBG imaging score and intraoperative hemodynamic fluctuations.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 159
- Patients with suspected PPGLs who received 131I-MIBG scintigraphy and were treated by surgery
-
- surgery was performed more than 6 months after 131I-MIBG scintigraphy; 2) tumor located in bladder where radioactive urine would influence assessment of tumor; 3) tumor was not resected as a whole; 4) resected tumor was not PPGLs confirmed by pathology; 5) 131I-MIBG scintigraphy images or intraoperative BP was not available for assessment.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Difference of SBP ARV and MAP ARV in Different Groups Intraoperative systolic blood pressure (SBP) and diastolic blood pressure (DBP) were recorded automatically in a 5 min interval from the beginning to the end of surgery. Mean arterial pressure (MAP) was calculated with the formula: MAP=1/3\*SBP+2/3\*DBP. ARV, which was defined as the average of absolute difference between successive BP values
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Peking union medical college hospital
🇨🇳Beijing, Beijing, China