A study to compare two drugs Gabapentin and Pregabalin as a premedicant drugs in a patients undergoing FESS surgeries.
Phase 3
- Conditions
- Health Condition 1: O- Medical and Surgical
- Registration Number
- CTRI/2021/09/036118
- Lead Sponsor
- DR Girisha C
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
ASA 1 &2
Weight- 40 to 70 kg
Airway- Mallampatti Grade 1 & 2
Normotensive patients
Orotracheal intubation only
Exclusion Criteria
History of allergy to study drugs.
Anticipated difficult intubation.
Laryngoscopy exceeding 20 seconds with normal airway.
Second attempt for intubation in normal airway.
Patients on sedatives,hypnotics and analgesics for chronic pain.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Attenuating pressor response to laryngoscopy and tracheal intubation.Timepoint: 0 ( during laryngoscopy) <br/ ><br>1,3,5 and 10 mins after intubation.
- Secondary Outcome Measures
Name Time Method AnxietyTimepoint: Before premedication <br/ ><br>1 hour after premedication;Sedation <br/ ><br>Timepoint: Before premedication <br/ ><br>1 hour after premedication;Side effectsTimepoint: Intra operative period <br/ ><br>every hour post operatively upto 12 hours