Creatine Supplementation on Cognition in Children

Not Applicable

• Conditions: Healthy
• Interventions: Dietary Supplement: Placebo; Dietary Supplement: creatine supplementation

• Registration Number: NCT01803230
• Lead Sponsor: University of Sao Paulo

Brief Summary

Creatine supplementation may improve cognitive function in elderly and vegetarian individuals. This study aims to investigate the role of creatine supplementation on cognitive function in healthy children.

Detailed Description

Not available

Basic Information
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Recruitment & Eligibility
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Study & Design
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Trial Locations

Study Timeline

• Status Verified: 2013-02
• Study Start: 2013-02
• Study First Submitted: 2013-02-27
• Study First Submitted QC: 2013-03-01
• Last Update Submitted: 2013-03-01
• Study First Posted: 2013-03-04
• Last Update Posted: 2013-03-04
• Primary Completion: 2015-02
• Study Completion: 2015-02

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

• healthy children
• age between 10 to 12 years of age

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Exclusion Criteria

• cognitive impairment
• vegetarian diet
• use of creatine in the past 6 months
• chronic kidney disease

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
placebo	Placebo	placebo (dextrose)
creatine	creatine supplementation	creatine supplementation

Primary Outcome Measures

Name	Time	Method
cognitive function	7 days	assessed by a battery of cognitive tests as follows: colors and words attention test, controlled words association test, memory and figures learning, mental flexibility test and inhibitory control, digit span test, and intelligence quotient.

Secondary Outcome Measures

Name	Time	Method
tissue creatine content	7 days	as assessed by 1H-MRS.

Trial Locations

Locations (1)

University of Sao Paulo; 🇧🇷 Sao Paulo, Brazil