Deep learning based MR Only Radiotherapy for head-and-neck cancer

• Conditions: hoofd-hals kanker; head and neck cancer

• Registration Number: NL-OMON49217
• Lead Sponsor: Erasmus MC, Universitair Medisch Centrum Rotterdam

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 15 April 2024

Recruitment & Eligibility

• Status: Pending
• Sex: Not specified
• Target Recruitment: 60

Inclusion Criteria

-Patients with head-and-neck cancer.
-Scheduled for primary (chemo)radiotherapy where a MRI scan is part of the
standard radiotherapy work up
-Written informed consent.

Exclusion Criteria

-Having any physical or mental status that interferes with the informed consent
procedure.
-Contraindications for MRI (e.g. claustrophobia, arterial clips in central
nervous system)

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Primary: the percentage of patients in the validation cohort for which the<br /><br>dosimetrical accuracy is within tolerance for at least 80% of the organs and<br /><br>targets when the synthetic CT is used for dose calculations. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Secondary: the percentage of patients in the validation cohort that meet for<br /><br>80% of the organs the criteria for contouring accuracy, namely that 80% of the<br /><br>contour points need to be within 2 mm from the gold standard contours. </p><br>