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Clinical Trials/NCT04275401
NCT04275401
Unknown
Not Applicable

Study on Quantitative Evaluation of Muscle Tone Using Elastic Ultrasound

Peking University Third Hospital1 site in 1 country40 target enrollmentDecember 1, 2019

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Muscle Tone Increased
Sponsor
Peking University Third Hospital
Enrollment
40
Locations
1
Primary Endpoint
shear wave elastography
Last Updated
5 years ago

Overview

Brief Summary

The test subjects were selected from patients with clinical manifestations in muscle tone and healthy volunteers. Elbow flexor is the main target muscle. Fifty patients and 50 healthy subjects were given three assessment methods to measure muscle tension: modified Ashworth rating scale, elastic ultrasound technology and surface electromyography, and the data obtained by these three methods will be statistically analyzed and discussed.

Registry
clinicaltrials.gov
Start Date
December 1, 2019
End Date
April 2022
Last Updated
5 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Mouwang Zhou

Professor

Peking University Third Hospital

Eligibility Criteria

Inclusion Criteria

  • There are clinical manifestations of changes in muscle tension of the elbow flexor group;
  • Subject's diagnosis is clear;
  • The degree of joint mobility meets the method of muscle tension assessment.

Exclusion Criteria

  • Has serious diseases such as heart, lung, liver, kidney, etc., cardiac function grade is greater than Grade I (NYHA), has symptoms and signs or examination results such as respiratory failure;
  • History of muscle disorders;
  • Recent (within 6 months) history of external injury, fracture or surgery of the limb;
  • Are using drugs that affect muscle tone;
  • Severe osteoporosis;
  • Acute phase of inflammation
  • Acute limb thrombosis of the subject;
  • Pregnancy.

Outcomes

Primary Outcomes

shear wave elastography

Time Frame: through study completion, an average of 1 year

use shear wave elastography to evaluate Young's modules of target muscles at each angle of the joint during the passive movement

surface electromyography

Time Frame: through study completion, an average of 1 year

use surface electromyography to evaluate average EMG, integrated electromyogram and root mean square of the target muscles

Modified Ashworth Scale

Time Frame: through study completion, an average of 1 year

Modified Ashworth Scale of the target muscles

Study Sites (1)

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