JPRN-UMIN000032916招募中未知
CPAP Effects on Atherosclerotic Plaques in Patients with Sleep-Disordered Breathing and Coronary Artery Disease - The ENTERPRISE trial
Department of Cardiovascular Medicine, Juntendo University School of Medicine, Tokyo, Japan0 个研究点目标入组 47 人开始时间: 2018年7月1日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 招募中
- 发起方
- 入组人数
- 47
研究概览
简要总结
Finally, the CPAP group (n=23) and non-CPAP group (n=24) were analyzed. Compared to the non-CPAP group, the CPAP group had a significantly decreased percentage atheroma volume (adjusted difference -2.81+/-1.10%, p=0.014) by analysis of covariance, and tended to have a lower incidence rate of MACCE, mainly driven by a decrease in target vessel revascularization (4% vs. 25%, p=0.097).
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 20years-old 至 75years-old（—）
- 性别
- All
入选标准
- 未提供
排除标准
- •1. Patients treated with CPAP therapy 2. Patients with hypersomnia requiring urgent treatment (defined as an Epworth Sleepiness Scale [ESS] score >18) 3. Patients over 75 years of age 4. Patients with New York Heart Association class II, III, or IV heart failure 5. Patients with renal insufficiency (serum creatinine 2.0 mg/dL) 6. Patients with hemodialysis 7. Patients with malignant disease 8. Patients recognized as inadequate by attending physician
研究者
相似试验
进行中（未招募）
不适用
ENTERPRISEPatients with stable coronary artery disease and sleep-disordered breathingPlaque progression and regressionJPRN-jRCTs032180281Dohi Tomotaka100
已完成
不适用
Effects of CPAP on Cardiovascular Risk in Obstructive Sleep Apnea (OSA) and Metabolic SyndromeObstructive Sleep ApneaMetabolic SyndromeNCT00635674Pavol Jozef Safarik University32
已完成
4 期
Effect of Continuous Positive Airway Pressure (CPAP) on Hypertension and Cardiovascular Morbidity-Mortality in Patients With Sleep Apnea and no Daytime SleepinessSleep ApneaCardiovascular DiseasesHypertensionNCT00127348Sociedad Española de Neumología y Cirugía Torácica700
已完成
不适用
Observational study to evaluate the relationship between lesion characteristics by optical coherence tomography in ACS patients and intra-individual lipid variabilityacute coronary syndromeJPRN-UMIN000039835Kobe University Hospital Cardiology296
已完成
不适用
Effect of CPAP on cardiometabolic biomarkers and cardiopulmonary performance in patients with obstructive sleep apneaObstructive sleep apneaTCTR20170810004Research Affair Faculty of Medicine Khon Kaen University40