Observational study to evaluate the relationship between lesion characteristics by optical coherence tomography in ACS patients and intra-individual lipid variability
- Conditions
- acute coronary syndrome
- Registration Number
- JPRN-UMIN000039835
- Lead Sponsor
- Kobe University Hospital Cardiology
- Brief Summary
ACS patients were categorized into a plaque rupture ACS (PR-ACS) group (n=44) or a non-plaque rupture ACS (NPR-ACS) group. Patients with ACS had significantly higher LDL-C levels and cVIM in LDL-C than the control group. The PR-ACS group had significantly higher mean LDL-C levels and greater cVIM in LDL-C than the control group. The PR-ACS group had a significantly higher cVIM than the NPR-ACS group. Multivariate analysis revealed that higher cVIM of LDL-C was an independent predictor of PR-ACS.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 296
Not provided
1, Patients who expressed refusal of participation of this study 2, Patients who were performed coronary intervention during the observational period 3, Patients whose culprit lesion has been expanded with a balloon of 2.75 mm or more until the first optical coherence tomography scan,
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method plaque rupture
- Secondary Outcome Measures
Name Time Method Clinical course Findings of optical coherence tomography