GBR With Ptfe With Bovine Bone With and Without Autogenous
- Conditions
- Atrophied Anterior Maxillary Ridges
- Interventions
- Other: Geistlich Bio-Oss® bovine bone alone
- Registration Number
- NCT03628157
- Lead Sponsor
- Cairo University
- Brief Summary
Ridge Augmentation in Atrophic Anterior Maxillary Ridges with a Titanium Reinforced Polytetraflouroethelene Membrane and Anorganic Bovine Bone-Derived Mineral in intervention group and Anorganic Bovine Bone-Derived Mineralwith Particulated Autogenous Bone Chips in control group.
CBCT will be done before surgery, immediate after surgery and 6 month to compare the bone gain in mm.
Bone sample will be collected during exposure after 6 month of surgery by trephine bur to assess the bone quality through histo-morphometric analysis in order to determine the size, shape and orientation of the bony trabeculae, the size and porosity of the bony cortex in addition to the new bone/ bone substitute ratio
* 1ry outcome: Amount of bone gain will be measured using linear measurements from CBCT immediate after surgery and after 6 month.
* 2ry outcome: a bone sample will be collected and analyzed under histo-morphometric analysis.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 10
-
• Patients with atrophied anterior maxillary ridge area.
- Age: 18 years and older.
- Both sexes.
- No intraoral soft and hard tissue pathology.
- No systemic condition that contraindicate bone augmentation
-
• Heavy smokers more than 20 cigarettes per day.(32)
- Patients with systemic disease that may affect normal healing.
- Psychiatric problems.
- Disorders to bone augmentation are related to history of radiation therapy to the head and neck neoplasia.
- Pregnant or nursing women.
- Patients with uncontrolled diabetes mellitus, rheumatoid arthritis or osteoporosis.
- Patient with previous history of radiotherapy.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description intervention Geistlich Bio-Oss® bovine bone alone using a bio-oss bovine bone alone control Geistlich Bio-Oss® bovine bone alone using a bio-oss bovine bone with autogenous bone ratio 1:1
- Primary Outcome Measures
Name Time Method Amount of bone gain (height and width in mm) 6 months will be measured using linear measurements from CBCT
- Secondary Outcome Measures
Name Time Method a bone sample will be collected and analyzed under histo-morphometric analysis. (no of bone cells in cubic mm) 6 months a bone sample will be collected and analyzed under histo-morphometric analysis.
Trial Locations
- Locations (1)
Faculty of Oral and Dental Medicine
🇪🇬Giza, Egypt