Posterior Maxillary Ridge Augmentation With Sinus Lift Using Mineralized Plasmatic Matrix Versus Autogenous Bone Graft

Not Applicable

• Conditions: Bone Resorption
• Interventions: Other: autogenous bone; Other: Mineralized plasmatic matrix

• Registration Number: NCT03014388
• Lead Sponsor: Cairo University

Brief Summary

Using growth factors obtained from patient's venous blood mixed with particulate autogenous bone the study compares bone gain by implant with gold standards in sinus Lift procedures for future implant insertion.

Detailed Description

To study the effectiveness of MPM in ridge augmentation with implant insertion compared with autogenous bone graft.

-PICO Population(P) : Patients with defective posterior maxillary alveolar ridge. Intervention (I) :Implant placement and ridge augmentation with MPM. Comparator (C) : Autogenous bone graft. Outcome (O) : Patient satisfaction - Implant stability.

Basic Information
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Recruitment & Eligibility
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Study & Design

Study Timeline

• Status Verified: 2016-12
• Study Start: 2017-01
• Study First Submitted: 2017-01-05
• Study First Submitted QC: 2017-01-05
• Last Update Submitted: 2017-01-05
• Study First Posted: 2017-01-09
• Last Update Posted: 2017-01-09
• Primary Completion: 2017-09
• Study Completion: 2017-10

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

1. Patients systemically free.
2. Patients with posterior maxillary defective ridges indicated for sinus lift procedure.
3. Cases with 5 mm bone height or less are included in the study.
4. Age between 18 and 50 years.
5. Both sexes.
6. Patients physically able to tolerate surgical and restorative procedures.
7. Good oral hygiene.
8. Highly motivated patients.

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Exclusion Criteria

1. Patients allergic to local anesthetic agent.
2. Medium and heavy smokers.
3. Pregnant females.
4. Presence of any pathosis in the pre-implant site.
5. Presence of any mucosal disease.
6. History of oral radiotherapy.
7. History of prolonged steroids use.
8. Psychological disorders.

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Autogenous bone graft (Gold Standard).	autogenous bone	Patients with defective posterior maxillary alveolar ridges requiring implant insertion will have Autogenous bone graft (Gold standard) and to be used for bone augmentation with sinus lift.
Mineralized Plasmatic Matrix (MPM)	Mineralized plasmatic matrix	Patients with defective posterior maxillary alveolar ridges requiring implant insertion will receive bone graft using Mineralized plasmatic matrix.

Primary Outcome Measures

Name	Time	Method
Patient Satisfaction regarding aesthetic results will be measured using questionnaire.	9 months	outcome will be measure using questionnaire.

Secondary Outcome Measures

Name	Time	Method
Stability of dental implants.	5 months	will be measured using OSTELL Device.