Effect of Acetaminophen on hemodynamic changes during intubatio

Phase 2

• Conditions: T88.4; Condition 1: Intubation. Condition 2: Hypospadias.; Failed or difficult intubation; Hypospadias

• Registration Number: IRCT20101220005426N10
• Lead Sponsor: Kerman University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 30 August 2021

Recruitment & Eligibility

• Status: Pending
• Sex: Male
• Target Recruitment: 126

Inclusion Criteria

Children undergoing hypospadias surgery
Children aged 2 to 7 years

Exclusion Criteria

Known allergy to Acetaminophen
Renal or hepatic impairment
Bleeding disorders
History of known heart or respiratory disease
History of seizures
Neurological or neuromuscular disorders
History of chronic pain or use of pain medication
Predict hard intubation

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Systolic blood pressure. Timepoint: Checking of systolic blood pressure before induction of anesthesia, after induction of anesthesia and at 1, 3, 6 and 9 minutes after intubation. Method of measurement: Patient monitoring system.;Diastolic blood pressure. Timepoint: Checking of diastolic blood pressure before induction of anesthesia, after induction of anesthesia and at 1, 3, 6 and 9 minutes after intubation. Method of measurement: Patient monitoring system.;Heart rate. Timepoint: Checking of heart rate before induction of anesthesia, after induction of anesthesia and at 1, 3, 6 and 9 minutes after intubation. Method of measurement: Patient monitoring system.;Incidence of nausea and vomiting. Timepoint: Evaluation of nausea and vomiting during recovery and 6 hours after recovery. Method of measurement: Ask the child or parents of the child.