Efficacy of intravenous immunoglobulin replacement therapy for hypogammaglobulinemia in severe infections
Not Applicable
- Conditions
- severe infectious diseases
- Registration Number
- JPRN-UMIN000032802
- Lead Sponsor
- Sapporo Medical University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 300
Inclusion Criteria
Not provided
Exclusion Criteria
1) A case of death or survival within 24 hours after admitting to the ICU 2) Child under 15 years old
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method prognosis (ICU mortality rate, 28 days mortality rate, 90-days mortality rate, hospital mortality rate)
- Secondary Outcome Measures
Name Time Method 1) characteristics of the patients 2) the severity of organ failure: SOFA score JAAM-DIC score 3) Serum IgG value and IVIG dosage at admitting to the ICU 4) Evaluation of reactivity to the treatment: Changes in SOFA score, Days of vasopressors, Length of ICU days, Hospitalized Days, ventilator days