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Clinical Trials/NCT04398810
NCT04398810
Unknown
Not Applicable

A Comparison of Postoperative Pain Results According to Pressure to Form Pneumoperitoneum During Robot-assisted Single-port Cholecystectomy; a Randomized Controlled Trial.

Seoul St. Mary's Hospital1 site in 1 country108 target enrollmentJune 2, 2020

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Cholecystitis
Sponsor
Seoul St. Mary's Hospital
Enrollment
108
Locations
1
Primary Endpoint
Visual Analogue Score(VAS)
Last Updated
5 years ago

Overview

Brief Summary

This study showed the difference in postoperative pain between the groups that performed surgery with the low-pressure pneumoperitoneum and the group that performed surgery in the standard-pressure pneumoperitoneum when robotic single-hole cholecystectomy was performed.

The primary purpose of the study was to compare the differences in the visual analog scale (VAS) between the two groups and to demonstrate the effectiveness of pain relief after surgery.

Secondly, the effect of the low-pressure pneumoperitoneum on the patient's postoperative recovery and outcome was compared with the control group by comparing the length of stay, operation time, and postoperative complications.

Detailed Description

Laparoscopic cholecystectomy was the most common treatment method for gallbladder-related diseases, and robotic cholecystectomy was also currently being performed. Many patients complained pain around the wound, shoulder and back after surgery. Several methods had been attempted to reduce postoperative pain, previous studies showed that oral medications such as NSAIDS, administration of local anesthetics in wounds and abdominal cavity, low-pressure penumoperitoneum, humidification of intraperitoneal washing fluid, And active residual gas suction in the abdominal cavity had been found to relieve postoperative pain. Robotic cholecystectomy, similar to laparoscopic cholecystectomy, also formed pneumoperitoneum to secure the surgical space during operation. Based on the results published in various studies, it had known that the most effective method of pain relief for laparoscopic pain was to create low-pressure pneumoperitoneum. In this study, investigators attempted to prove the effectiveness of low pressure pneumoperioneum through a prospective randomized controlled trial between the experimental group with the low-pressure pneumoperitoneum and the control group with the standard-pressure pneumoperitoneum during robotic single-hole cholecystectomy.

Registry
clinicaltrials.gov
Start Date
June 2, 2020
End Date
December 30, 2021
Last Updated
5 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Taeho Hong

Professor

Seoul St. Mary's Hospital

Eligibility Criteria

Inclusion Criteria

  • Patients who underwent elective gallbladder surgery
  • Cholelithiasis
  • Chronic cholecystitis
  • Gallbladder polyps
  • Gallbladder adenoma
  • Porcelain gallbladder

Exclusion Criteria

  • Acute cholecystitis patient group
  • Necrotic gallbladder
  • Collapsed gallbladder
  • Gallbladder pustosis
  • Gallbladder emphysema
  • Hemorrhagic gallbladder
  • Perforated gallbladder
  • cholecystitis with a gallbladder thickness of 4 mm or more on CT or ultrasound
  • cholecystitis with adhesions to surrounding organs due to inflammation of the gallbladder
  • Patient group performing surgery concurrently due to other organ diseases

Outcomes

Primary Outcomes

Visual Analogue Score(VAS)

Time Frame: 24 hours after surgery

The Visual Analogue Scale (VAS) consists of a straight line with the endpoints defining extreme limits such as 'no pain at all' and 'pain as bad as it could be'. The patient is asked to mark his pain level on the line between the two endpoints. The distance between 'no pain at all' and the mark then defines the subject's pain.

Secondary Outcomes

  • postoperative complication(Participants will be followed for the duration of hospital stay, an expected average of 2 days)
  • hospital stay(Participants will be followed for the duration of hospital stay, an expected average of 2 days)
  • operation time(Participants will be followed for the duration of hospital stay, an expected average of 2 days)

Study Sites (1)

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