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An Efficacy Study of a Single Dose Treatment of PRO-513 for Subjects Suffering a Migraine Attack

Phase 3
Completed
Conditions
Migraine
Photophobia
Phonophobia
Registration Number
NCT00330850
Lead Sponsor
ProEthic Pharmaceuticals
Brief Summary

The purpose of the study is to show the efficacy of a single dose of PRO-513 for treating subjects suffering moderate pain form a migraine attack, with or without aura. The study is also intended to show the effectiveness of PRO-513 for associated symptoms of nausea, photophobia, and phonophobia due to a migraine attack.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
650
Inclusion Criteria
  • Male and Female subjects
  • 18-65 years of age
  • Primary diagnosis of migraine attack with aura or migraine attack without aura
  • Migraine history of averaging at least 1 migraine attack per month but averaging not more than 6 migraine attacks per month over the prior year
  • Female subjects must use an effective form of birth control
  • Listing of additional inclusion criteria are available through the Sponsor
Exclusion Criteria
  • Excluding subjects with a history of other serious events causing secondary headaches
  • Excluding subjects with a current medical condition that could interfere with the overall study intent or affect the absorption, distribution, metabolism, or excretion of the study medication
  • Excluding subjects with a history or current medical condition that could confound the study results or use of a concomitant medication that could interfere with the study drug
  • Listing of additional exclusion criteria are available through the Sponsor

Study & Design

Study Type
INTERVENTIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (16)

Mercy Health Research

🇺🇸

St. Louis, Missouri, United States

Diamond Headache Clinic

🇺🇸

Chicago, Illinois, United States

DermResearch, Inc.

🇺🇸

Austin, Texas, United States

LCFP Inc.

🇺🇸

Ft. Myers, Florida, United States

International Research Center

🇺🇸

Towson, Maryland, United States

The Innovative Clinical Research Center

🇺🇸

Alexandria, Virginia, United States

Headache Wellness Center

🇺🇸

Greensboro, North Carolina, United States

Associated Neurologists of Southern CT

🇺🇸

Fairfield, Connecticut, United States

Palm Beach Neurological Center

🇺🇸

Palm Beach Gardens, Florida, United States

New York Headache Center

🇺🇸

New York, New York, United States

Michigan Head-Pain and Neurologic Institute

🇺🇸

Ann Arbor, Michigan, United States

New England Center for Headache

🇺🇸

Stamford, Connecticut, United States

Road Runner Research, Ltd.

🇺🇸

San Antonio, Texas, United States

J&S Studies, Inc.

🇺🇸

Bryan, Texas, United States

Houston Headache Clinic

🇺🇸

Houston, Texas, United States

Advanced Healthcare, S.C.

🇺🇸

Milwaukee, Wisconsin, United States

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